Chen, Chien-Fu

陳建甫教授

陳建甫教授現任國立臺灣大學應用力學研究所特聘教授，並兼任臺大奈米機電系統研究中心主任。他的研究興趣與專長涵蓋精密機械製程於生化檢測與材料科學的應用、攜帶式醫療檢測系統及奈米科技在環境監控與醫學中的應用。此外，陳教授也對於先進半導體製程中試劑分析裝置的開發著墨甚多。陳教授在半導體製程與醫學應用領域有著豐富的研究經驗，研究成果也發表在國內外眾多優良學術期刊。相關的研究應用更獲得國科會未來科技獎、英國皇家化學會會士的殊榮。

  • 著作：
  1. Chien, Y.-S., Tsai, T.-T., Lin, J.-H., Chang, C.-C., & Chen, C.-F. (2024). One-step copper deposition-induced signal amplification for multiplex bacterial infection diagnosis on a lateral flow immunoassay device. Biosensors and Bioelectronics, 267, 116849–116849. https://doi.org/10.1016/j.bios.2024.116849
  2. Tung, C.-Y., Tsai, T.-T., Chiu, P.-Y., Viter, R., Ramanavičius, A., Yu, C.-J., & Chen, C.-F. (2024). Diagnosis of Mycobacterium tuberculosis using palladium–platinum bimetallic nanoparticles combined with paper-based analytical devices. Nanoscale, 16(12), 5988–5998. https://doi.org/10.1039/d3nr05508f
  3. Chen, W.-T., Yan, C.-F., Yu, C.-J., Liao, Y.-C., & Chen, C.-F. (2024). Highly catalytic Prussian blue analogues and their application on the three-dimensional origami paper-based sweat sensors. Biosensors & Bioelectronics/Biosensors & Bioelectronics (Online), 254, 116188–116188. https://doi.org/10.1016/j.bios.2024.116188
  4. Chiou, Y., Pang, H., Huang, Y., & Chen, C. (2023). A Semi‐Automatic Environmental Monitoring Device for Mercury and Cobalt Ion Detection. Small, 20(8). https://doi.org/10.1002/smll.202303871
  5. Pilvenyte, G., Ratautaitė, V., Raimonda Boguzaite, Simonas Ramanavičius, Chen, C.-M., Viter, R., & Arūnas Ramanavičius. (2023). Molecularly Imprinted Polymer-Based Electrochemical Sensors for the Diagnosis of Infectious Diseases. Biosensors, 13(6), 620–620. https://doi.org/10.3390/bios13060620
  6. Chen, W.-T., Chiu, P.-Y., & Chen, C.-F. (2023). A flash signal amplification approach for ultrasensitive and rapid detection of single nucleotide polymorphisms in tuberculosis. Biosensors and Bioelectronics, 237, 115514–115514. https://doi.org/10.1016/j.bios.2023.115514
  7. Chu, W.-Y., Chiou, Y.-R., Luo, R.-H., Chen, T.-H., Yu, C.-J., Chou, Y.-J., Chang, H.-T., & Chen, C.-F. (2023). Partially miscible droplet microfluidics to enhance interfacial adsorption of hydrophilic nanoparticles for colloidosome synthesis. Chemical Engineering Journal, 471, 144223–144223. https://doi.org/10.1016/j.cej.2023.144223
  8. Liao, Y.-M., Chiu, P.-Y., Chien, Y.-S., & Chen, C.-F. (2023). Music Box-Inspired Semi-Automatic Hematocrit Validation Device. ACS Sensors, 8(8), 2952–2959. https://doi.org/10.1021/acssensors.3c00129
  9. Drobysh, M., Ramanaviciene, A., Viter, R., Chen, C.-F., Samukaite-Bubniene, U., Ratautaite, V., & Ramanavicius, A. (2022). Biosensors for the Determination of SARS-CoV-2 Virus and Diagnosis of COVID-19 Infection. International Journal of Molecular Sciences, 23(2), 666. https://doi.org/10.3390/ijms23020666
  10. Maryia Drobysh, Viktorija Liustrovaite, Ausra Baradoke, Viter, R., Chen, C.-F., Arunas Ramanavicius, & Arunas Ramanavicius. (2022). Determination of rSpike Protein by Specific Antibodies with Screen-Printed Carbon Electrode Modified by Electrodeposited Gold Nanostructures. 12(8), 593–593. https://doi.org/10.3390/bios12080593
  11. Chu, W.-Y., Yang, C.-H., Viter, R., Arũnas Ramanavičius, Luo, S.-C., & Chen, C.-F. (2022). Monolith-modified cellulose paper for biochemical sensing applications. Sensors & Diagnostics, 1(5), 994–1002. https://doi.org/10.1039/d2sd00108j
  12. Wu, S., Tsai, T.-T., Li, T.-H., Dung, C.-Y., Chiu, P.-Y., Lin, J.-H., & Chen, C.-F. (2022). Palladium-platinum bimetallic nanomaterials and their application in Staphylococcus aureus detection on paper-based devices. Biosensors and Bioelectronics, 216, 114669–114669. https://doi.org/10.1016/j.bios.2022.114669
  13. Chen, C.-A., Yuan, H., Chen, C.-W., Chien, Y.-S., Sheng, W.-H., & Chen, C.-F. (2021). An electricity- and instrument-free infectious disease sensor based on a 3D origami paper-based analytical device. Lab on a Chip, 21(10), 1908–1915. https://doi.org/10.1039/d1lc00079a
  14. Yuan, H., Tian, J., Chao, Y., Chien, Y.-S., Luo, R.-H., Guo, J.-Y., Li, S., Chou, Y.-J., Shum, H. C., & Chen, C.-F. (2021). Hand-Powered Microfluidics for Parallel Droplet Digital Loop-Mediated Isothermal Amplification Assays. ACS Sensors, 6(8), 2868–2874. https://doi.org/10.1021/acssensors.1c00184
  15. Hao, Y., Chiu, P.-Y., & Chen, C.-F. (2021). Paper-based analytical devices for point-of-care blood tests. 15(4). https://doi.org/10.1063/5.0055601
  16. Poon, S. H. L., Wong, W. H. L., Lo, A. C. Y., Yuan, H., Chen, C.-F., Jhanji, V., Chan, Y. K., & Shih, K. C. (2021). A systematic review on advances in diagnostics for herpes simplex keratitis. Survey of Ophthalmology, 66(3), 514–530. https://doi.org/10.1016/j.survophthal.2020.09.008
  17. Lin, J.-H., Tsai, T.-T., Zeng, Q., Chang, C.-Y., Guo, J.-Y., Lin, C.-J., & Chen, C.-F. (2020). A Multifunctional Microfluidic Device for Blood Typing and Primary Screening of Blood Diseases. ACS Sensors, 5(10), 3082–3090. https://doi.org/10.1021/acssensors.0c00969
  18. Li Wen Hsu, Yu Hsuan Lin, Jun Yu Guo, Chien Fu Chen, Yi Ju Chou, & Yi Chun Yeh. (2020). Simultaneous Determination of l-Phenylalanine, Phenylethylamine, and Phenylacetic Acid Using Three-Color Whole-Cell Biosensors within a Microchannel Device. ACS Applied Bio Materials, 3(8), 5120–5125. https://doi.org/10.1021/acsabm.0c00590
  19. Chou, Y.-J., Hung, C.-Y., & Chen, C.-F. (2019). Formation of drops and rings in double-diffusive sedimentation. Journal of Fluid Mechanics, 884. https://doi.org/10.1017/jfm.2019.946
  20. Chen, C.-A., Yeh, W.-S., Tsai, T.-T., Li, Y.-D., & Chen, C.-F. (2019). Three-dimensional origami paper-based device for portable immunoassay applications. Lab on a Chip, 19(4), 598–607. https://doi.org/10.1039/c8lc01255e
  21. Tsai, T.-T., Chen, C.-A., Ho, N. Y.-J., Yang, S., & Chen, C.-F. (2019). Fluorescent Double-Stranded DNA-Templated Copper Nanoprobes for Rapid Diagnosis of Tuberculosis. ACS Sensors, 4(11), 2885–2892. https://doi.org/10.1021/acssensors.9b01163
  22. Tsai, T.-T., Huang, T.-H., Ho, N. Y.-J., Chen, Y.-P., Chen, C.-A., & Chen, C.-F. (2019). Development of a multiplex and sensitive lateral flow immunoassay for the diagnosis of periprosthetic joint infection. Scientific Reports, 9(1), 15679. https://doi.org/10.1038/s41598-019-52051-6
  23. Liu, C.-H., Chen, C.-A., Chen, S.-J., Tsai, T.-T., Chu, C.-C., Chang, C.-C., & Chen, C.-F. (2019). Blood Plasma Separation Using a Fidget-Spinner. Analytical Chemistry, 91(2), 1247–1253. https://doi.org/10.1021/acs.analchem.8b04860
  24. Tsai, T.-T., Huang, T.-H., Chen, C.-A., Ho, N. Y.-J., Chou, Y.-J., & Chen, C.-F. (2018). Development a stacking pad design for enhancing the sensitivity of lateral flow immunoassay. Scientific Reports, 8(1). https://doi.org/10.1038/s41598-018-35694-9
  25. Yang, C.-H., Chen, C.-A., & Chen, C.-F. (2018). Surface-modified cellulose paper and its application in infectious disease diagnosis. Sensors and Actuators B Chemical, 265, 506–513. https://doi.org/10.1016/j.snb.2018.03.092
  26. Guo, K.-H., Chen, P.-H., Lin, C., Chen, C.-F., Lee, I-Ren., & Yeh, Y.-C. (2018). Determination of Gold Ions in Human Urine Using Genetically Engineered Microorganisms on a Paper Device. ACS Sensors, 3(4), 744–748. https://doi.org/10.1021/acssensors.7b00931
  27. Peng, Z., Ng, A. L., Kwon, H., Wang, P., Chen, C.-F., Lee, C. S., & Wang, Y. (2017). Graphene as a functional layer for semiconducting carbon nanotube transistor sensors. Carbon, 125, 49–55. https://doi.org/10.1016/j.carbon.2017.09.031
  28. Tsai, T.-T., Huang, C.-Y., Chen, C.-A., Shen, S., Wang, M.-C., & Cheng, C.-M. (2017). Diagnosis of Tuberculosis Using Colorimetric Gold Nanoparticles on a Paper-Based Analytical Device. ACS Sensors, 2(9), 1345–1354. https://doi.org/10.1021/acssensors.7b00450
  29. Ng, A. L., Chen, C.-F., Kwon, H., Peng, Z., Lee, Cheng. S., & Wang, Y. (2017). Chemical Gating of a Synthetic Tube-in-a-Tube Semiconductor. Journal of the American Chemical Society, 139(8), 3045–3051. https://doi.org/10.1021/jacs.6b12111
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